the potential for serious adverse reactions in nursing infants from methazolamide, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug. Indications Dosage, indications, methazolamide is indicated in the treatment of ocular conditions where lowering intraocular pressure is likely to be of therapeutic benefit, such as chronic open-angle glaucoma, secondary glaucoma, and preoperatively in acute angle-closure glaucoma where lowering the intraocular pressure is desired before surgery. Methazolamide (trade name, neptazane ) is a potent carbonic anhydrase inhibitor. Not applicable US Methazolamide Tablet 50 mg/1 Oral Carilion Materials Management Not applicable US Methazolamide Tablet 25 mg/1 Oral Paddock Laboratories, LLC Not applicable US Methazolamide Tablet 25 mg/1 Oral Teva US Methazolamide Tablet 50 mg/1 Oral Fera Pharmaceuticals US Methazolamide Tablet 25 mg/1 Oral. General References Iyer GR, Bellantone RA, Taft DR: In vitro characterization of the erythrocyte distribution of methazolamide: a model of erythrocyte transport and binding kinetics. Renal clearance accounts for 20 to 25 of the total clearance of drug.
Detailed Methazolamide dosage information for adults. Includes dosages for Glaucoma; plus renal, liver and dialysis adjustments.
Find Lowest Prices on, methazolamide, tablets, USP, description. This coupon is not insurance and is not valid in combination with any government-sponsored drug plans. Peak plasma concentrations are observed 1 to 2 hours after dosing. The free m Methazolamide Coupon and Discount Card can save you up to 75* off your prescription prices. Gene Name CA1 Uniprot ID P00915 Uniprot Name Carbonic anhydrase 1 Molecular Weight 28870.0 Da References Ilies MA, Masereel B, Rolin S, Scozzafava A, Campeanu G, Cimpeanu V, Supuran CT: Carbonic anhydrase inhibitors: aromatic and heterocyclic sulfonamides incorporating adamantyl moieties with strong anticonvulsant activity. Gene Name CYP3A4 Uniprot ID P08684 Uniprot Name Cytochrome P450 3A4 Molecular Weight 57342.67 Da References Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including. StevensJohnson syndrome induced by methazolamide treatment". PubMed: Enzymes Kind Protein Organism Humans Pharmacological action Unknown Actions Inhibitor Curator comments The data currently available for this enzyme inhibition is limited to one in vitro study. Use: Treatment of ocular conditions where lowering intraocular pressure is likely to be of therapeutic benefit, such as chronic open-angle glaucoma, secondary glaucoma, and preoperatively in acute angle-closure glaucoma. Involved in the regulation of fluid secretion.